Lmna knockout mouse embryonic fibroblasts are less contractile than their wild-type counterparts
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چکیده
منابع مشابه
Atm heterozygous mice are more sensitive to radiation-induced cataracts than are their wild-type counterparts.
It is important to know whether the human population includes genetically predisposed radiosensitive subsets. In vitro studies have shown that cells from individuals homozygous for ataxia telangiectasia (A-T) are much more radiosensitive than cells from unaffected individuals. Although cells heterozygous for the ATM gene (ATM(+/-)) may be slightly more radiosensitive in vitro, it remained to be...
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Control of size and shape is a challenge in nanoparticle synthesis. Synthetic and biosynthetic (both extracellular and intracellular) methods are used to prepare silver nanoparticle (SNP). In this study, the behavior of three strains of Staphylococcus aureus (S. aureus) was investigated in the presence of silver nitrate intra- and extracellularly. S. aureus strains biosynthesized SNPs intracell...
متن کاملDoes Biosynthetic Silver Nanoparticles Are More Stable With Lower Toxicity than Their Synthetic Counterparts?
Control of size and shape is a challenge in nanoparticle synthesis. Synthetic and biosynthetic (both extracellular and intracellular) methods are used to prepare silver nanoparticle (SNP). In this study, the behavior of three strains of Staphylococcus aureus (S. aureus) was investigated in the presence of silver nitrate intra- and extracellularly. S. aureus strains biosynthesized SNPs intracell...
متن کاملCD14+ antigen-presenting cells in human dermis are less mature than their CD1a+ counterparts.
We recently demonstrated that three antigen-presenting cell (APC) subsets exist in the healthy human dermis, CD14(+) and CD1a(+) dermal APCs and migratory dermal Langerhans cells. Here, we extend these findings by defining CD208 as an exclusive marker of migratory dermal Langerhans cells, confirming that migratory dermal Langerhans cells (CD1a(high) CD207(+) CD208(+)) and CD1a(+) dermal APCs (C...
متن کاملPiper betle induces phase I & II genes through Nrf2/ARE signaling pathway in mouse embryonic fibroblasts derived from wild type and Nrf2 knockout cells
BACKGROUND Nuclear factor-erythroid 2 p45 related factor 2 (Nrf2) is a primary transcription factor, protecting cells from oxidative stress by regulating a number of antioxidants and phase II detoxifying enzymes. Dietary components such as sulforaphane in broccoli and quercetin in onions have been shown to be inducers of Nrf2. Piper betle (PB) grows well in tropical climate and the leaves are u...
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ژورنال
عنوان ژورنال: Integrative Biology
سال: 2017
ISSN: 1757-9694,1757-9708
DOI: 10.1039/c7ib00069c